Cardiovascular Recombinant Proteins
Human Ephrin-A1/EFNA1 Recombinant Protein (RPES2986)
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- SKU:
- RPES2986
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cardiovascular
Description
system_update_altDatasheet
Human Ephrin-A1/EFNA1 Recombinant Protein
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.
| Product Name: | Human Ephrin-A1/EFNA1 Recombinant Protein (RPES2986) |
| Product Code: | RPES2986 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Ephrin-A1, EPH-Related Receptor Tyrosine Kinase Ligand 1, LERK-1, Immediate Early Response Protein B61, Tumor Necrosis Factor Alpha-Induced Protein 4, TNF Alpha-Induced Protein 4, EFNA1, EPLG1, LERK1, TNFAIP4 |
| Accession: | P20827 |
| Sequence: | Asp19-Ser182 |
| Fusion tag: | C-Fc |
| Activity: | Immobilized Human EphA2-His(Cat: PKSH032009) at 4µg/ml(100 ?l/well) can bind Human EFNA1-Fc. The ED50 of Human EFNA1-Fc is 0.03ug/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ephrin-A1 is produced by our Mammalian expression system and the target gene encoding Asp19-Ser182 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 46.5 kDa |
| AP Mol Mass: | 55-60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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