Human EphB4/HTK Recombinant Protein (RPES5098)
- SKU:
- RPES5098
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human EphB4/HTK Recombinant Protein
Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein of the ephrin receptor subfamily in the protein kinase superfamily. Members of the ephrin and Eph families are mainly contact-dependent local mediators in development and maturity that regulate cell function by means of largely contact-dependent mechanisms. Furthermore, EphB4 protein and its ligand Ephrin-B2 promote tumour growth in several human cancer types. EphB4 protein has tumour suppressing potential and cell proliferation control, as well as extracellular matrix remodelling and invasive capability. Therefore; Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers. Human EphB4/HTK Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human EphB4/HTK Recombinant Protein (RPES5098) |
| Product Code: | RPES5098 |
| Size: | 100µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | HTK,MYK1,TYRO11 |
| Accession: | NP_004435.3 |
| Sequence: | Met 1-Ala 539 |
| Fusion tag: | |
| Activity: | Measured by its binding ability in a functional ELISA. Immobilized human EphB4 at 2 µg/ml (100 ?l/well) can bind human EphrinB2 with a linear range of 1-125 ng/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | The mature form of human EphB4 (NP_004435.3) extracellular domain (Met 1-Ala 539) with quinary-aa peptide (DDDDK) at the C-terminus was expressed and purified. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 57.7 kDa |
| AP Mol Mass: | 65-70 kDa |
| Formulation: | Lyophilized from sterile 100mM NaCl; 50mM Tris; pH 7.5 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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