Enzymes Recombinant Proteins

Human ENTPD3 Recombinant Protein (RPPB1622)

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SKU:
RPPB1622
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O75355
Research Area:
Enzymes

Description

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Product Name:Human ENTPD3 Recombinant Protein
Product Code:RPPB1622
Size:5µg
Species:Human
Target:ENTPD3
Synonyms:Ectonucleoside Triphosphate Diphosphohydrolase 3, CD39L3, Ecto-ATP Diphosphohydrolase 3, CD39 Antigen-Like 3, Ecto-ATPDase 3, Ecto-Apyrase 3, Ecto-ATPase 3, EC 3.6.1.5, NTPDase 3, HB6, NTPDase-3.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:ENTPD3 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:ADLQIHKQEV LPPGLKYGIV LDAGSSRTTV YVYQWPAEKE NNTGVVSQTF KCSVKGSGIS SYGNNPQDVP RAFEECMQKV KGQVPSHLHG STPIHLGATA GMRLLRLQNE TAANEVLESI QSYFKSQPFD FRGAQIISGQ EEGVYGWITA NYLMGNFLEK NLWHMWVHPH GVETTGALDL GGASTQISFV AGEKMDLNTS DIMQVSLYGY VYTLYTHSFQ CYGRNEAEKK FLAMLLQNSP TKNHLTNPCY PRDYSISFTM GHVFDSLCTV DQRPESYNPN DVITFEGTGD PSLCKEKVAS IFDFKACHDQ ETCSFDGVYQ PKIKGPFVAF AGFYYTASAL NLSGSFSLDT FNSSTWNFCS QNWSQLPLLL PKFDEVYARS YCFSANYIYH LFVNGYKFTE ETWPQIHFEK EVGNSSIAWS LGYMLSLTNQ IPAESPLIRL PIEPPHHHHHH

Ectonucleoside Triphosphate Diphosphohydrolase 3, also known as ENTPD3, which owns a threefold preference for the hydrolysis of ATP over ADP is similar to E-type nucleotidases (NTPases). ENTPD3 is a protein coding gene which contains four apyrase-conserved areas which is characteristic of NTPases.

ENTPD3 Human Recombinant produced in in Sf9 Baculovirus cells is a single, non-glycosylated polypeptide chain containing 451 amino acids (44-485a.a) and having a molecular mass of 50.7kDa (Migrates at 50-70kDa on SDS-PAGE under reducing conditions). ENTPD3 is fused to a 6 amino acids His-tag at C-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:ENTPD3: Has a threefold preference for the hydrolysis of ATP over ADP. Belongs to the GDA1/CD39 NTPase family.
UniProt Protein Details:

Protein type:Hydrolase; EC 3.6.1.5; Membrane protein, integral; Phosphatase (non-protein); Nucleotide Metabolism - purine; Membrane protein, multi-pass; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 3p21.3

Molecular Function:protein binding

NCBI Summary:This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]
UniProt Code:O75355
NCBI GenInfo Identifier:115311595
NCBI Gene ID:956
NCBI Accession:O75355.2
UniProt Secondary Accession:O75355,O60495, Q8N6K2, B2R8D0, G5E9N0,
UniProt Related Accession:O75355
Molecular Weight:50,762 Da
NCBI Full Name:Ectonucleoside triphosphate diphosphohydrolase 3
NCBI Synonym Full Names:ectonucleoside triphosphate diphosphohydrolase 3
NCBI Official Symbol:ENTPD3��
NCBI Official Synonym Symbols:HB6; CD39L3; NTPDase-3��
NCBI Protein Information:ectonucleoside triphosphate diphosphohydrolase 3
UniProt Protein Name:Ectonucleoside triphosphate diphosphohydrolase 3
UniProt Synonym Protein Names:CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPDase 3; Ecto-ATPase 3; Ecto-apyrase 3; HB6
Protein Family:Ectonucleoside triphosphate diphosphohydrolase
UniProt Gene Name:ENTPD3��
UniProt Entry Name:ENTP3_HUMAN
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