Enzymes Recombinant Proteins

Human ELAC1 Recombinant Protein (RPPB1610)

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SKU:
RPPB1610
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9H777
Research Area:
Enzymes

Description

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Product Name:Human ELAC1 Recombinant Protein
Product Code:RPPB1610
Size:10µg
Species:Human
Target:ELAC1
Synonyms:ElaC Ribonuclease Z 1, D29, ElaC Homolog Protein 1, TRNA 3 Endonuclease 1, TRNA Z (Short Form), Ribonuclease Z 1, Deleted In Ma29, EC 3.1.26.11, TRNase Z 1, RNaseZ(S), RNase Z 1, Zinc Phosphodiesterase ELAC Protein 1, TRNA 3 Processing Endoribonuclease, ElaC (E. Coli) Homolog 1, ElaC Homolog 1 (E. Coli), ElaC Homolog 1, TRNase ZS, ELAC1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:ELAC1 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 80.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSMDVTF LGTGAAYPSP TRGASAVVLR CEGECWLFDC GEGTQTQLMK SQLKAGRITK IFITHLHGDH FFGLPGLLCT ISLQSGSMVS KQPIEIYGPV GLRDFIWRTM ELSHTELVFH YVVHELVPTA DQCPAEELKE FAHVNRADSP PKEEQGRTIL LDSEENSYLL FDDEQFVVKA FRLFHRIPSF GFSVVEKKRP GKLNAQKLKD LGVPPGPAYG KLKNGISVVL ENGVTISPQD VLKKPIVGRK ICILGDCSGV VGDGGVKLCF EADLLIHEAT LDDAQMDKAK EHGHSTPQMA ATFAKLCRAK RLVLTHFSQR YKPVALAREG ETDGIAELKK QAESVLDLQE VTLAEDFMVI SIPIKK

ElaC Ribonuclease Z 1, also known as ELAC1 is a member of the RNase Zfamily.� Zinc phosphodiesterase, which showssome tRNA 3'-processing endonuclease activity. In addition, ELAC1 is implicatedin tRNA maturation, by removing a 3'-trailer from precursor tRNA.

ELAC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 386 amino acids (1-363 a.a) and having a molecular mass of 42.4 kDa.ELAC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ELAC1: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Belongs to the RNase Z family.Protein type: EC 3.1.26.11; RibonucleaseChromosomal Location of Human Ortholog: 18q21Cellular Component: cytosol; nucleusMolecular Function: 3'-tRNA processing endoribonuclease activity
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9H777
NCBI GenInfo Identifier:41017799
NCBI Gene ID:55520
NCBI Accession:Q9H777.2
UniProt Secondary Accession:Q9H777,Q9NS99
UniProt Related Accession:Q9H777
Molecular Weight:40,019 Da
NCBI Full Name:Zinc phosphodiesterase ELAC protein 1
NCBI Synonym Full Names:elaC ribonuclease Z 1
NCBI Official Symbol:ELAC1��
NCBI Official Synonym Symbols:D29��
NCBI Protein Information:zinc phosphodiesterase ELAC protein 1
UniProt Protein Name:Zinc phosphodiesterase ELAC protein 1
UniProt Synonym Protein Names:Deleted in Ma29; ElaC homolog protein 1; Ribonuclease Z 1; RNase Z 1; tRNA 3 endonuclease 1; tRNase Z 1
Protein Family:Zinc phosphodiesterase ELAC protein
UniProt Gene Name:ELAC1��
UniProt Entry Name:RNZ1_HUMAN
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