Cell Biology Recombinant Proteins
Human EGR1 Recombinant Protein (RPES2623)
- SKU:
- RPES2623
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
Description
Human EGR1 Recombinant Protein
EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of synaptobrevin II (a protein important for synaptic exocytosis).
| Product Name: | Human EGR1 Recombinant Protein (RPES2623) |
| Product Code: | RPES2623 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | EGR-1, Early growth response protein 1, Zif268, zinc finger protein 225, NGFI-A , nerve growth factor-induced protein A, |
| Accession: | P18146 |
| Sequence: | Gln282-Ser433 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Early growth response protein 1 is produced by our E.coli expression system and the target gene encoding Gln282-Ser433 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 19.9 kDa |
| AP Mol Mass: | 18 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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