Enzymes Recombinant Proteins

Human ECHDC1 Recombinant Protein (RPPB1605)

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SKU:
RPPB1605
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9NTX5
Research Area:
Enzymes

Description

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Product Name:Human ECHDC1 Recombinant Protein
Product Code:RPPB1605
Size:20µg
Species:Human
Target:ECHDC1
Synonyms:Ethylmalonyl-CoA decarboxylase, Enoyl-CoA hydratase domain-containing protein 1, Methylmalonyl-CoA decarboxylase, MMCD, ECHDC1, dJ351K20.2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The ECHDC1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 1mM DTT and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MALKQEMAKS LLKTASLSGR TKLLHQTGLS LYSTSHGFYE EEVKKTLQQF PGGSIDLQKE DNGIGILTLN NPSRMNAFSG VMMLQLLEKV IELENWTEGK GLIVRGAKNT FSSGSDLNAV KSLGTPEDGM AVCMFMQNTL TRFMRLPLIS VALVQGWALGGGAEFTTACD FRLMTPESKI RFVHKEMGII PSWGGTTRLV EIIGSRQALK VLSGALKLDS KNALNIGMVE EVLQSSDETK SLEEAQEWLK QFIQGPPEVI RALKKSVCSG RELYLEEALQ NERDLLGTVW GGPANLEAIA KKGKFNK

Enoyl CoA hydratase domain containing 1 (ECHDC1) is a member of the enoyl-CoA hydratase/isomerase family. ECHDC1 is an enzyme which hydrates the double bond between the second and third carbons on acyl-CoA. The ECHDC1 enzyme is crucial to metabolizing fatty acids to supply both acetyl CoA and energy.

SNAP25 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 226 amino acids (1-206 a.a.) and having a molecular mass of 25.4 kDa. SNAP25 is fused to a 20 amino acid His Tag at N-terminus and purified by conventional chromatography techniques.

UniProt Protein Function:ECHDC1: Decarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activityx at lower level. Belongs to the enoyl-CoA hydratase/isomerase family. 6 isoforms of the human protein are produced by alternative splicing.Protein type: EC 4.1.1.41; EC 4.1.1.94Chromosomal Location of Human Ortholog: 6q22.33Cellular Component: cytosolMolecular Function: carboxy-lyase activity
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9NTX5
NCBI GenInfo Identifier:124007138
NCBI Gene ID:55862
NCBI Accession:Q9NTX5.2
UniProt Secondary Accession:Q9NTX5,Q5TEF6, Q5TEF7, Q5TEG0, Q5TEG4, Q9NZ30, A6NFJ5 B7Z8S0, E9PEN7, E9PR31
UniProt Related Accession:Q9NTX5
Molecular Weight:31,089 Da
NCBI Full Name:Ethylmalonyl-CoA decarboxylase
NCBI Synonym Full Names:ethylmalonyl-CoA decarboxylase 1
NCBI Official Symbol:ECHDC1��
NCBI Official Synonym Symbols:MMCD; HEL-S-76; dJ351K20.2��
NCBI Protein Information:ethylmalonyl-CoA decarboxylase
UniProt Protein Name:Ethylmalonyl-CoA decarboxylase
UniProt Synonym Protein Names:Enoyl-CoA hydratase domain-containing protein 1; Methylmalonyl-CoA decarboxylase (EC:4.1.1.41); MMCD
Protein Family:Ethylmalonyl-CoA decarboxylase
UniProt Gene Name:ECHDC1��
UniProt Entry Name:ECHD1_HUMAN
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