Enzymes Recombinant Proteins

Human DUSP23 Recombinant Protein (RPPB1599)

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SKU:
RPPB1599
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BVJ7
Research Area:
Enzymes

Description

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Product Name:Human DUSP23 Recombinant Protein
Product Code:RPPB1599
Size:10µg
Species:Human
Target:DUSP23
Synonyms:Dual specificity protein phosphatase 23, Low molecular mass dual specificity phosphatase 3, LDP-3, VH1-like phosphatase Z, DUSP23, LDP3, VHZ, VH1-Like Member Z, EC 3.1.3.16, EC 3.1.3.48, DUSP25, MOSP, LDP3, Dual Specificity Phosphatase 23, VH1-Like Phosphatase Z, LDP-3, VHZ, Low-Molecular-Mass Dual-Specificity Phosphatase 3, Low Molecular Mass Dual Specificity Phosphatase 3, Dual Specificity Protein, Phosphatase 23, Testicular Tissue Protein Li 59.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:DUSP23 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 10% glycerol and 100mM NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK
Biological Activity:Specific activity is > 200 units/mg, and is defined as the amount of enzyme that hydrolyzes 1.0 nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37�C.

DUSP23 is a member of the protein-tyrosine phosphatase family. DUSP23 is a protein phosphatase which facilitates dephosphorylation of phosphorylated proteins on Tyr and Ser/Thr residues. In vitro, DUSP23 dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10). In addition, DUSP23 enhances activation of JNK and p38(MAPK14).

DUSP23 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 170 amino acids (1-150 a.a) and having a molecular mass of 18.8kDa.DUSP23 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9BVJ7
NCBI GenInfo Identifier:73620828
NCBI Gene ID:54935
NCBI Accession:Q9BVJ7.1
UniProt Secondary Accession:Q9BVJ7,Q9NX48
UniProt Related Accession:Q9BVJ7
Molecular Weight:16,588 Da
NCBI Full Name:Dual specificity protein phosphatase 23
NCBI Synonym Full Names:dual specificity phosphatase 23
NCBI Official Symbol:DUSP23��
NCBI Official Synonym Symbols:VHZ; MOSP; LDP-3; DUSP25��
NCBI Protein Information:dual specificity protein phosphatase 23
UniProt Protein Name:Dual specificity protein phosphatase 23
UniProt Synonym Protein Names:Low molecular mass dual specificity phosphatase 3; LDP-3; VH1-like phosphatase Z
Protein Family:Dual specificity protein phosphatase
UniProt Gene Name:DUSP23��
UniProt Entry Name:
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