Human DLG4 / PSD95 ELISA Kit

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SKU:
HUFI01144
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P78352
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
DLG4, Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90
Reactivity:
Human
Research Area:
Cell Biology

Description

Human DLG4 / PSD95 ELISA Kit

The membrane-associated guanylate kinase (MAGUK) family is represented by DLG4/PSD95. It is recruited into NMDA receptor and potassium channel clusters after heteromultimerizing with another MAGUK protein, DLG2. These two MAGUK proteins may form a multimeric scaffold for the clustering of receptors, ion channels, and associated signalling proteins at postsynaptic sites. Intellectual Developmental Disorder, Autosomal Dominant 62 and Encephalopathy, Progressive, Early-Onset, With Episodic Rhabdomyolysis are two diseases linked to DLG4. Pathways related to DLG4/PSD95 include RET signalling and Post NMDA receptor activation events.

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