Immune Checkpoint Recombinant Proteins

Human DKK1 Recombinant Protein (hFc Tag) (HDPT0168)

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SKU:
HDPT0168
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human DKK1 Recombinant Protein (hFc Tag)

Description:This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines.
Product name:Human DKK1 Recombinant Protein (hFc Tag)
Synonyms:DKK-1, SK
Type:protein
Size:50 µg
Name:DKK1
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 90%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:DKK1(Thr32-His266)+hFc(Glu99-Ala330)
Gene ID:22943
Uniprot:O94907
Molecular Weight:70 kDa
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