Metabolism Recombinant Proteins

Human Dipeptidase 1/DPEP1 Recombinant Protein (RPES2375)

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SKU:
RPES2375
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism

Description

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Human Dipeptidase 1/DPEP1 Recombinant Protein

Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics; such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However; DPEP1 expression decreased with pathological differentiation; lymph-node and distant metastasis.

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