Cell Death Recombinant Proteins

Human DFFA Recombinant Protein (RPES2441)

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SKU:
RPES2441
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death

Description

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Human DFFA Recombinant Protein

DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.

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