Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.
Product Name:
Human Dermatopontin/DPT Recombinant Protein (RPES2249)
Product Code:
RPES2249
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP and DPT,
Accession:
Q07507
Sequence:
Gln19-Val201
Fusion tag:
C-Fc-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Dermatopontin is produced by our Mammalian expression system and the target gene encoding Gln19-Val201 is expressed with a Fc, 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
49.9 kDa
AP Mol Mass:
53 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Human Dermatopontin ELISADPT (Dermatopontin) is a Protein Coding gene. Among other things, it encodes a protein that is thought to be involved in transporting melanin granules throughout the length...