Human Dectin/CLEC7A Recombinant Protein (RPES0195)

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SKU:
RPES0195
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Dectin/CLEC7A Recombinant Protein

Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a transmembrane protein that binds beta-1,3 and beta-1,6 glucans, is expressed on most cells of the immune system's innate component, and has been linked to phagocytosis as well as fungal killing by macrophages, neutrophils, and dendritic cells. Dectin-1 recognizes beta-glucan and activates an effective immune response, including phagocytosis and proinflammatory factor production, to eliminate fungal infections that are especially beneficial in immunocompromised patients. It is also found in the adaptive immune response, autoimmune diseases, and immune tolerance. Dectin-1 can identify and react to live fungal infections, and it is being recognized as having a vital role in the body's natural defences. Dectin-1 can also interact with an unknown endogenous ligand on T cells and function as a co-stimulatory protein in addition to exogenous ligands. Dectin-1 plays a role in anti-fungal immunity, as well as in mice and humans, and it is possible that this receptor may play a part in regulating mycobacterial infections. Human Dectin/CLEC7A Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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