Enzymes Recombinant Proteins

Human DECR2 Recombinant Protein (RPPB1566)

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SKU:
RPPB1566
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9NUI1
Research Area:
Enzymes

Description

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Product Name:Human DECR2 Recombinant Protein
Product Code:RPPB1566
Size:10µg
Species:Human
Target:DECR2
Synonyms:Peroxisomal 2,4-dienoyl-CoA reductase, pDCR, 2,4-dienoyl-CoA reductase 2, DECR2, PDCR, SDR17C1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The DECR2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAQPPPD VEGDDCLPAY RHLFCPDLLR DKVAFITGGG SGIGFRIAEI FMRHGCHTVI ASRSLPRVLT AARKLAGATG RRCLPLSMDV RAPPAVMAAV DQALKEFGRI DILINCAAGN FLCPAGALSF NAFKTVMDID TSGTFNVSRV LYEKFFRDHG GVIVNITATL GNRGQALQVH AGSAKAAVDA MTRHLAVEWG PQNIRVNSLA PGPISGTEGL RRLGGPQASL STKVTASPLQ RLGNKTEIAH SVLYLASPLA SYVTGAVLVA DGGAWLTFPN GVKGLPDFAS FSAKL

Peroxisomal 2,4-dienoyl-CoA reductase (DECR2) is an supporting enzyme of beta-oxidation. DECR2 partakes in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. DECR2 catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.

DECR2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 315 amino acids (1-292) and having a molecular mass of 33.2kDa.DECR2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
UniProt Code:Q9NUI1
NCBI GenInfo Identifier:10190704
NCBI Gene ID:26063
NCBI Accession:NP_065715.1
UniProt Secondary Accession:Q9NUI1,Q6ZRS7, Q96ET0,
UniProt Related Accession:Q9NUI1
Molecular Weight:30 kDa
NCBI Full Name:peroxisomal 2,4-dienoyl-CoA reductase
NCBI Synonym Full Names:2,4-dienoyl-CoA reductase 2
NCBI Official Symbol:DECR2��
NCBI Official Synonym Symbols:PDCR; SDR17C1��
NCBI Protein Information:peroxisomal 2,4-dienoyl-CoA reductase
UniProt Protein Name:Peroxisomal 2,4-dienoyl-CoA reductase
UniProt Synonym Protein Names:2,4-dienoyl-CoA reductase 2; Short chain dehydrogenase/reductase family 17C member 1
UniProt Gene Name:DECR2��
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