Human DBNDD2 Recombinant Protein (RPPB3330)

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SKU:
RPPB3330
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BQY9

Description

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Product Name:Human DBNDD2 Recombinant Protein
Product Code:RPPB3330
Size:10µg
Species:Human
Target:DBNDD2
Synonyms:Dysbindin domain-containing protein 2, Casein kinase-1 binding protein, CK1BP, HSMNP1, DBNDD2, C20orf35.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:DBNDD2 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMDPNPR AALERQQLRL RERQKFFEDI LQPETEFVFP LSHLHLESQR PPIGSISSME VNVDTLEQVE LIDLGDPDAA DVFLPCEDPP PTPQSSGMDN HLEELSLPVP TSDRTTSRTS SSSSSDSSTN LHSPNPSDDG ADTPLAQSDE EEERGDGGAE PGACS

Dysbindin domain-containing protein 2 (DBNDD2) is a member of the dysbindin family. DBNDD2 regulates the activity of casein kinase-1 and inhibits CSNK1D autophosphorylation (in vitro). DBNDD2 also interacts with CSNK1D and CSNK1E. DBNDD2 is detected in brain.

DBNDD2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids (1-161 a.a) and having a molecular mass of 20.1kDa (Molecular weight on SDS-PAGE will appear higher).DBNDD2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:DBNDD2: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro). Belongs to the dysbindin family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 20q13.12Cellular Component: synaptic vesicle membraneMolecular Function: protein bindingBiological Process: negative regulation of protein kinase activity; neurite development
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9BQY9
NCBI GenInfo Identifier:115299745
NCBI Gene ID:55861
NCBI Accession:NP_001041686.1
UniProt Secondary Accession:Q9BQY9,Q331S6, Q5QPV4, Q5QPV6, Q9BQZ0, Q9BVL1, Q9H1F6 Q9NWZ0, Q9NY07, Q9NZ31
UniProt Related Accession:Q9BQY9
Molecular Weight:33.48kD
NCBI Full Name:dysbindin domain-containing protein 2 isoform a
NCBI Synonym Full Names:dysbindin domain containing 2
NCBI Official Symbol:DBNDD2��
NCBI Official Synonym Symbols:CK1BP; HSMNP1; C20orf35��
NCBI Protein Information:dysbindin domain-containing protein 2
UniProt Protein Name:Dysbindin domain-containing protein 2
UniProt Synonym Protein Names:Casein kinase-1 binding protein; CK1BP; HSMNP1
Protein Family:Dysbindin domain-containing protein
UniProt Gene Name:DBNDD2��
UniProt Entry Name:
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