Human DAB1 / Disabled homolog 1 ELISA Kit

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SKU:
HUFI01145
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O75553
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
DAB1, Disabled homolog 1
Reactivity:
Human
Research Area:
Developmental Biology

Description

Human DAB1 / Disabled homolog 1 ELISA Kit

Normal cognitive function necessitates the laminar organisation of multiple neuronal types in the cerebral cortex. The disabled-1 gene is involved in brain development in mice, directing cortical neurons to migrate past previously formed neurons to reach their proper layer. The protein encoded by DAB1/Disabled homolog 1 is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain, and it is similar to disabled-1. Spinocerebellar Ataxia 37 and Spastic Ataxia are two diseases linked to DAB1. Lipoprotein metabolism, Guidance Cues, and Growth Cone Motility are all related pathways to DAB1/Disabled homolog 1.

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