Human D-amino-acid oxidase / DAO ELISA Kit

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SKU:
HUFI01264
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P14920
Sensitivity:
0.469ng/ml
Range:
0.781-50ng/ml
ELISA Type:
Sandwich
Synonyms:
DAO, D-amino-acid oxidase, DAAO, DAMOX
Reactivity:
Human
Research Area:
Cell Biology

Description

Human D-amino-acid oxidase / DAO ELISA Kit

There are a number of D-amino acids that act as substrates, with the exception of naturally occurring L-amino acids. D-amino-acid oxidase/DAO biological purpose is unknown; it may function as a detoxifying agent by removing D-enzyme from tissues during aging. It degrades D-serine, a co-agonist of the NMDA receptor, in mice. D-amino-acid oxidase/DAO may be involved in the pathogenesis of schizophrenia. Amyotrophic Lateral Sclerosis 1 and Bipolar Disorder are examples of diseases linked to DAO. Glyoxylate metabolism and glycine degradation, as well as viral mRNA Translation, are among the pathways influenced by D-amino-acid oxidase/DAO.

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