Human Cytokeratin 6a / KRT6A ELISA Kit

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SKU:
HUFI00870
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P02538
Sensitivity:
18.75pg/ml
Range:
31.25-2000pg/ml
ELISA Type:
Sandwich
Synonyms:
KRT6A, KeRatin, type II cytoskeletal 6A, K6A, CK-6A, CK-6D, Type-II keRatin Kb6, KeRatin-6A, CytokeRatin-6A, CytokeRatin-6D, KRT6D
Reactivity:
Human
Research Area:
Cell Biology

Description

Human Cytokeratin 6a / KRT6A ELISA Kit

Cytokeratin 6a is a member of the keratin family. The type II cytokeratins are basic or neutral proteins grouped in heterotypic keratin chains coexpressed during the differentiation of simple and stratified epithelial tissues. There are six distinct types of this type II cytokeratin (KRT6), with as many as six genes. The genes are activated in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and glandular epithelia. The KRT6 gene in particular codes for the most prevalent form of the protein. Pachyonychia congenita has been linked to genetic changes in these genes. Peptides derived from the C-terminal portion of the protein have antibacterial activity. Pachyonychia congenita 3 and Pachyonychia Congenita 1 are examples of KRT6A-related illnesses.

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