Human CXCR4 Full-Length Bioactive Membrane Protein (HDFP055)

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SKU:
HDFP055
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P61073

Description

system_update_altDatasheet
Product nameHuman CXCR4 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP055
Product CategoryFull Length Transmembrane Proteins
Target:CXCR4
Uniprot:P61073
Description:Human CXCR4 full length protein-synthetic nanodisc
Molecular Weight:The human full length CXCR4 protein has a MW of 39.7 kDa
Protein Family:Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane
Protein Pathways:Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Leukocyte transendothelial migration
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:A CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.
Delivery:In Stock
UsageResearch use only
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