Chemokines Recombinant Proteins

Human CXCL7/NAP-2 Recombinant Protein (RPES1406)

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RPES1406

Description

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Human CXCL7/NAP-2 Recombinant Protein

Human Chemokine (C-X-C motif) Ligand 7 (CXCL7); also known as neutrophil activating peptide 2 (NAP-2); is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). CXCL7 binds CXCR2, which is similar to other ELR chemokines such as IL-8 and the GRO proteins; it attracts and activates neutrophils. CXCL7; Connective Tissue Activating Protein III (CTAPIII) and beta thrombogulin (beta-TG); are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. However, because beta TG, CTAPIII, and PBP are amino-terminal extended versions of NAP2 with the same CXC chemokine domains as NAP2, they do not have CXCL7/NAP2 activity. CXCL7 activates CXCR-2, which is a G protein-coupled receptor. Human CXCL7/NAP-2 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

Product Name:Human CXCL7/NAP-2 Recombinant Protein (RPES1406)
Product Code:RPES1406
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Platelet Basic Protein, PBP, C-X-C Motif Chemokine 7, Leukocyte-Derived Growth Factor, LDGF, Macrophage-Derived Growth Factor, MDGFSmall-Inducible Cytokine B7, PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1
Accession:P02775
Sequence:Ala59-Asp128
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human C-X-C Motif Chemokine 7 is produced by our E.coli expression system and the target gene encoding Ala59-Asp128 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:7.6 kDa
AP Mol Mass:9 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Chemokines
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