Chemokines Recombinant Proteins
Human CXCL1 Recombinant Protein (RPES1222)
- SKU:
- RPES1222
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Chemokines
Description
Human CXCL1 Recombinant Protein
Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.
| Product Name: | Human CXCL1 Recombinant Protein (RPES1222) |
| Product Code: | RPES1222 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Growth-Regulated Alpha Protein, C-X-C Motif Chemokine 1, GRO-Alpha(1-73), Melanoma Growth Stimulatory Activity, MGSA, Neutrophil-Activating Protein 3, NAP-3, CXCL1, GRO, GRO1, GROA, MGSA, SCYB1 |
| Accession: | P09341 |
| Sequence: | Ala35-Asn107 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human C-X-C Motif Chemokine 1 is produced by our Mammalian expression system and the target gene encoding Ala35-Asn107 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 8.9 kDa |
| AP Mol Mass: | 14 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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