Immune Checkpoint Recombinant Proteins

Human CXC-R3 Recombinant Protein (hFc Tag) (HDPT0233)

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SKU:: HDPT0233
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human CXC-R3 Recombinant Protein (hFc Tag)

Description:	This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
Product name:	Human CXC-R3 Recombinant Protein (hFc Tag)
Synonyms:	C-X-C chemokine receptor type 3,CXC-R3,CXCR-3,CKR-L2，G protein-coupled receptor 9，CD183，IP-10 receptor
Type:	protein
Size:	50 µg
Name:	CXC-R3
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	Contact Technical Support
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-Human Fc
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	CXC-R3(Met1-Arg53)+hFc(Glu99-Ala330)
Gene ID:
Uniprot:	P49682
Molecular Weight:	31.35 kDa

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