Human CX3CR1 Full-Length Bioactive Membrane Protein (HDFP096)

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SKU:
HDFP096
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P49238

Description

system_update_altDatasheet
Product nameHuman CX3CR1 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP096
Product CategoryFull Length Transmembrane Proteins
Target:CX3CR1
Uniprot:P49238
Description:Human CX3CR1 full length protein-synthetic nanodisc
Molecular Weight:The human full length CX3CR1 protein has a MW of 40.8 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Delivery:3-4 weeks
UsageResearch use only
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