Human CUTA Recombinant Protein (RPPB3313)

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SKU:
RPPB3313
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O60888

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human CUTA Recombinant Protein
Product Code:RPPB3313
Size:25µg
Species:Human
Target:CUTA
Synonyms:ACHAP, C6orf82, MGC111154, cutA divalent cation tolerance homolog, CUTA.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:CUTA Human solution containing 20mM Tris-HCl pH-8, 1mM DTT, and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MRLLLLPRVL LTMASGSPPT QPSPASDSGS GYVPGSVSAA FVTCPNEKVA KEIARAVVEK RLAACVNLIP QITSIYEWKG KIEEDSEVLM MIKTQSSLVP ALTDFVRSVH PYEVAEVIAL PVEQGNFPYL QWVRQVTESV SDSITVLPLE HHHHHH

CUTA is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. CUTA participates in cellular tolerance to a broad range of divalent cations other than copper. The CUTA protein is a cytoplasmic protein, encoded by the single-gene operon and has been related to divalent cation tolerance.

CUTA Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 156 amino acids (33-179 a.a.) and having a molecular mass of 17.1 kDa. CUTA protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography.

UniProt Protein Function:CUTA: May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE). Belongs to the CutA family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 6p21.32

Cellular Component: membrane

Molecular Function:protein binding; enzyme binding

Biological Process: response to metal ion; protein localization

UniProt Code:O60888
NCBI GenInfo Identifier:62286491
NCBI Gene ID:51596
NCBI Accession:O60888.2
UniProt Secondary Accession:O60888,Q3B784, Q5JXM9, Q5SU05, Q9NYQ9, A2AB26, A2BEL4
UniProt Related Accession:O60888
Molecular Weight:179
NCBI Full Name:Protein CutA
NCBI Synonym Full Names:cutA divalent cation tolerance homolog (E. coli)
NCBI Official Symbol:CUTA��
NCBI Official Synonym Symbols:ACHAP; C6orf82��
NCBI Protein Information:protein CutA; divalent cation tolerant protein CUTA; acetylcholinesterase-associated protein; brain acetylcholinesterase putative membrane anchor
UniProt Protein Name:Protein CutA
UniProt Synonym Protein Names:Acetylcholinesterase-associated protein; Brain acetylcholinesterase putative membrane anchor
Protein Family:Cutinase
UniProt Gene Name:CUTA��
UniProt Entry Name:CUTA_HUMAN
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system_update_altDatasheetHuman CUTA Recombinant Protein Protein CutA (CUTA) posseses a signal peptide and is widely expressed in brain. CUTA mayforms part of a complex of membrane proteins attac