Human CSF2RA/GM-CSFR Recombinant Protein (RPES1140)

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SKU:
RPES1140
Product Type:
Recombinant Protein
Species:
Human

Description

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Human CSF2RA/GM-CSFR Recombinant Protein

Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit ? (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).

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