Immune Checkpoint Recombinant Proteins

Human CSF1R Recombinant Protein (His Tag) (HDPT0052)

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SKU:: HDPT0052
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human CSF1R Recombinant Protein (His Tag)

Description:	The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.
Product name:	Human CSF1R Recombinant Protein (His Tag)
Synonyms:	CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR
Type:	protein
Size:	50 µg
Name:	CSF1R
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	> 95%
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C- 6×His tag
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	CSF1R（Ile20-Leu514）+6×His tag
Gene ID:	1436
Uniprot:	P07333
Molecular Weight:	55.6 kDa