Description
| Product Name: | Human CSDC2 Recombinant Protein |
| Product Code: | RPPB3276 |
| Size: | 10µg |
| Species: | Human |
| Target: | CSDC2 |
| Synonyms: | Cold shock domain-containing protein C2, RNA-bindingprotein PIPPin, PIPPIN, DJ347H13.2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CSDC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSH MGSMTSESTSPPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFSRSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWSGQVVGS |
| UniProt Code: | Q9Y534 |
Cold shock domain-containing protein C2 (CSDC2) is RNA-binding factor that binds specifically to the very 3'-UTR ends of both histone H1 and H3. 3 mRNAs encompass the polyadenylation signal. The CSDPs (cold shock domain containing proteins) are one group of the evolutionarily conserved nucleic acid-binding proteins extensively distributed in bacteria, plants, animals, and involved in a variety of cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. CSDC2 has a central role in the negative regulation of histone variant synthesis in the developing brain.
CSDC2 Human Recombinant produced in E.coli is a single,non-glycosylated polypeptide chain containing 176 amino acids (1-153) andhaving a molecular mass of 19.2kDa. CSDC2 is fused to a 23 amino acid His-tagat N-terminus.