Enzymes Recombinant Proteins

Human CRYZL1 Recombinant Protein (RPPB1506)

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SKU:
RPPB1506
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O95825
Research Area:
Enzymes

Description

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Product Name:Human CRYZL1 Recombinant Protein
Product Code:RPPB1506
Size:25µg
Species:Human
Target:CRYZL1
Synonyms:Quinone Oxidoreductase-like Protein 1, Quinone oxidoreductase homolog 1, Zeta-crystallin homolog, Protein 4P11, QOH-1, CRYZL1, 4P11.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:CRYZL1 solution containing 20mM Tris-HCl buffer (pH8.0), 2mM DTT, 0.1M NaCl and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MKGLYFQQSS TDEEITFVFQ EKEDLPVTED NFVKLQVKAC ALSQINTKLL AEMKMKKDLF PVGREIAGIV LDVGSKVSFF QPDDEVVGIL PLDSEDPGLC EVVRVHEHYL VHKPEKVTWT EAAGSIRDGV RAYTALHYLS HLSPGKSVLI MDGASAFGTI AIQLAHHRGA KVISTACSLE DKQCLERFRP PIARVIDVSN GKVHVAESCL EETGGLGVDI VLDAGVRLYS KDDEPAVKLQ LLPHKHDIIT LLGVGGHWVT TEENLQLDPP DSHCLFLKGA TLAFLNDEVW NLSNVQQGKY LCILKDVMEK LSTGVFRPQL DEPIPLYEAK VSMEAVQKNQ GRKKQVVQF

Quinone Oxidoreductase (CRYZL1) is a protein that has sequence similarity to zeta crystalline. CRYZL1 has NADPH-dependent quinone reductase activity distinct from other known quinone reductases, and may have a role as a pH response element-binding protein. CRYZL1 contains an NAD(P)H binding site. CRYZL1 is expressed at different levels in the heart, brain, skeletal muscle, kidney, pancreas, liver and lung. CRYZL1 is present at low levels in human lens tissue.

CRYZL1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 369 amino acids (1-349 a.a.) and having a molecular mass of 40.8 kDa. CRYZL1 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:CRYZL1: a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]Protein type: EC 1.-.-.-; OxidoreductaseChromosomal Location of Human Ortholog: 21q21.3Cellular Component: cytosol
UniProt Protein Details:
NCBI Summary:This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]
UniProt Code:O95825
NCBI GenInfo Identifier:115502443
NCBI Gene ID:9946
NCBI Accession:O95825.2
UniProt Secondary Accession:O95825,Q96DY0, Q9NVY7, B2RDX1, B3KQ77
UniProt Related Accession:O95825
Molecular Weight:21,928 Da
NCBI Full Name:Quinone oxidoreductase-like protein 1
NCBI Synonym Full Names:crystallin zeta like 1
NCBI Official Symbol:CRYZL1��
NCBI Official Synonym Symbols:4P11; QOH-1��
NCBI Protein Information:quinone oxidoreductase-like protein 1
UniProt Protein Name:Quinone oxidoreductase-like protein 1
UniProt Synonym Protein Names:Protein 4P11; Quinone oxidoreductase homolog 1; QOH-1; Zeta-crystallin homolog
Protein Family:Quinone oxidoreductase-like protein
UniProt Gene Name:CRYZL1��
UniProt Entry Name:QORL1_HUMAN
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