Alpha-crystallinA chain/CRYAA is a heat shock protein (HSP20) family member that acts as a molecular chaperone. Microcornea syndrome and Cataract are two examples of diseases linked to CRYAA. The control of deltaF508 CFTR degradation in CF is regulated by the alpha-crystallinA chain/CRYAA pathway. Human CRYAA Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human CRYAA Recombinant Protein (RPES3185)
Product Code:
RPES3185
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Alpha-Crystallin A Chain, Heat Shock Protein Beta-4, HspB4, Alpha-Crystallin A Chain, Short Form, CRYAA, CRYA1, HSPB4
Accession:
P02489
Sequence:
Met 1-Ser173
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human alpha-Crystallin A Chain is produced by our E.coli expression system and the target gene encoding Met1-Ser173 is expressed with a 6His tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
20.9 kDa
AP Mol Mass:
20 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, 2mM EDTA, pH 8.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.