Metabolism Recombinant Proteins
Human CROT Recombinant Protein (RPES4320)
- SKU:
- RPES4320
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Metabolism
Description
Human CROT Recombinant Protein
Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine acyltransferase belonging to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. Carnitine octanoyltransferase (CROT or COT) facilitate the transport of medium- and long-chain fatty acids through the peroxisomal and mitochondrial membranes. It is physiologically inhibited by malonyl-CoA. COT also has functions in efficiently converting one of the end products of the peroxisomal beta-oxidation of pristanic acid, 4, 8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
| Product Name: | Human CROT Recombinant Protein (RPES4320) |
| Product Code: | RPES4320 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | COT |
| Accession: | Q9UKG9 |
| Sequence: | Met 1-Leu 612, 474 Leu/Val |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human CROT (Q9UKG9) (Met 1-Leu 612, 474 Leu/Val) was fused with a polyhistidine tag at the C-terminus. |
| Purity: | > 93 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 71.5 kDa |
| AP Mol Mass: | 65 kDa |
| Formulation: | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glycerol |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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