Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not contain a predicted signal sequence or transmembrane domains. CPNE1 may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 has a broad tissue distribution and it may function in membrane trafficking.
Product Name:
Human Copine/CPNE1 Recombinant Protein (RPES1021)
Product Code:
RPES1021
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Copine-1, Copine I, CPN1, CPNE1
Accession:
Q99829
Sequence:
Met 1-Ala537
Fusion tag:
N,C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Copine-1 is produced by our E.coli expression system and the target gene encoding Met1-Ala537 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
62.2 kDa
AP Mol Mass:
70 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB?150mM NaCl,pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.