Description
Product Name: | Human CMC1 Recombinant Protein |
Product Code: | RPPB3211 |
Size: | 20µg |
Species: | Human |
Target: | CMC1 |
Synonyms: | C3orf68, Cmc1p, COX assembly mitochondrial protein homolog. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile Filtered clear solution. |
Formulation: | CMC1 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.4M UREA and 10% glycerol. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 85.0% as determined by SDS-PAGE. |
Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMALDPAD QHLRHVEKDV LIPKIMREKA KERCSEQVQD FTKCCKNSGV LMVVKCRKEN SALKECLTAY YNDPAFYEEC KMEYLKEREE FRKTGIPTKK RLQKLPTSM |
COX Assembly Mitochondrial Protein 1(CMC1) is a member of the CMC family. CMC1 is required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. CMC1 attaches copper and might be involved in copper trafficking and distribution to COX and SOD1.
CMC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 129 amino acids (1-106 a.a.) and having a molecular mass of 14.9kDa.CMC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
UniProt Protein Function: | CMC1: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. Binds copper. May be involved in copper trafficking and distribution to COX and SOD1. Belongs to the CMC family.Chromosomal Location of Human Ortholog: 3p24.1Cellular Component: mitochondrion |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q7Z7K0 |
NCBI GenInfo Identifier: | 30851665 |
NCBI Gene ID: | 152100 |
NCBI Accession: | BC052644 |
UniProt Secondary Accession: | Q7Z7K0,Q68DJ7 |
UniProt Related Accession: | Q7Z7K0 |
Molecular Weight: | 12,490 Da |
NCBI Full Name: | Homo sapiens COX assembly mitochondrial protein homolog (S. cerevisiae), mRNA |
NCBI Synonym Full Names: | C-X9-C motif containing 1 |
NCBI Official Symbol: | CMC1�� |
NCBI Official Synonym Symbols: | C3orf68�� |
NCBI Protein Information: | COX assembly mitochondrial protein homolog |
UniProt Protein Name: | COX assembly mitochondrial protein homolog |
UniProt Synonym Protein Names: | |
Protein Family: | COX assembly mitochondrial protein |
UniProt Gene Name: | CMC1�� |
UniProt Entry Name: | COXM1_HUMAN |