Description
| Product Name: | Human CMC1 Recombinant Protein |
| Product Code: | RPPB3211 |
| Size: | 20µg |
| Species: | Human |
| Target: | CMC1 |
| Synonyms: | C3orf68, Cmc1p, COX assembly mitochondrial protein homolog. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CMC1 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.4M UREA and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMALDPAD QHLRHVEKDV LIPKIMREKA KERCSEQVQD FTKCCKNSGV LMVVKCRKEN SALKECLTAY YNDPAFYEEC KMEYLKEREE FRKTGIPTKK RLQKLPTSM |
COX Assembly Mitochondrial Protein 1(CMC1) is a member of the CMC family. CMC1 is required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. CMC1 attaches copper and might be involved in copper trafficking and distribution to COX and SOD1.
CMC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 129 amino acids (1-106 a.a.) and having a molecular mass of 14.9kDa.CMC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CMC1: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. Binds copper. May be involved in copper trafficking and distribution to COX and SOD1. Belongs to the CMC family.Chromosomal Location of Human Ortholog: 3p24.1Cellular Component: mitochondrion |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q7Z7K0 |
| NCBI GenInfo Identifier: | 30851665 |
| NCBI Gene ID: | 152100 |
| NCBI Accession: | BC052644 |
| UniProt Secondary Accession: | Q7Z7K0,Q68DJ7 |
| UniProt Related Accession: | Q7Z7K0 |
| Molecular Weight: | 12,490 Da |
| NCBI Full Name: | Homo sapiens COX assembly mitochondrial protein homolog (S. cerevisiae), mRNA |
| NCBI Synonym Full Names: | C-X9-C motif containing 1 |
| NCBI Official Symbol: | CMC1�� |
| NCBI Official Synonym Symbols: | C3orf68�� |
| NCBI Protein Information: | COX assembly mitochondrial protein homolog |
| UniProt Protein Name: | COX assembly mitochondrial protein homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | COX assembly mitochondrial protein |
| UniProt Gene Name: | CMC1�� |
| UniProt Entry Name: | COXM1_HUMAN |