Human CLDN1 / Claudin-1 ELISA Kit

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SKU:
HUFI02327
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O95832
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
CLDN1, Senescence-associated epithelial membrane protein, CLD1, claudin 1, ILVASC, CLD1, CLDN1, SEMP1, claudin 1, claudin-1, CLD1, ILVASC, Senescence-associated epithelial membrane protein, SEMP1, senescence-associated epithelial membrane protein 1
Reactivity:
Human
Research Area:
Immunology

Description

Human CLDN1 / Claudin-1 ELISA

CLDN1 (Claudins) are integral membrane proteins that form tight junctions in epithelial cells. They are composed of four transmembrane domains, two extracellular loops, and two intracellular loops. Claudins determine paracellular permeability and selectivity and play key roles in various biological processes including maintenance of cell polarity, regulation of epithelial proliferation and differentiation, tumorigenesis, and intestinal barrier function. Diseases associated with CLDN1 include Epidermolysis Bullosa, Junctional, Herlitz Type and Laryngocele.

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