Enzymes Recombinant Proteins

Human CKS2 Recombinant Protein (RPPB2487)

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SKU:
RPPB2487
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P33552
Research Area:
Enzymes

Description

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Product Name:Human CKS2 Recombinant Protein
Product Code:RPPB2487
Size:25µg
Species:Human
Target:CKS2
Synonyms:CDC28, CKSHS2, CKS2, CDC28 Protein Kinase 2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The CKS2 protein solution contains 20mM Tris-HCl pH-7.5 and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVPKT HLMSEEEWRRLGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQ

CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is necessary for their biological function. The CKS2 mRNA is expressed in various patterns through the cell cycle in HeLa cells, which shows spcific role for the encoded protein. CKS2 (CDC28) Protein kinase 2 binds to the catalytic subunit of cyclin-dependent kinases and has thus in involved in cell cycle regulation. CKS2 is required for the first metaphase/anaphase transition during the meiosis. An increase in expression of CKS2 protects the cells from apoptosis. CKS2 is essential during early embryogenesis and cell cycle progression in somatic cells.

CKS2 Human Recombinant fused to T7-Tag produced in E.Coli is a single, non- glycosylated polypeptide chain containing 94 amino acids and having a molecular mass of 11 kDa.

UniProt Code:P33552
NCBI GenInfo Identifier:461747
NCBI Gene ID:1164
NCBI Accession:P33552.1
UniProt Secondary Accession:P33552,Q6FGI9, Q6LET5,
UniProt Related Accession:P33552
Molecular Weight:79
NCBI Full Name:Cyclin-dependent kinases regulatory subunit 2
NCBI Synonym Full Names:CDC28 protein kinase regulatory subunit 2
NCBI Official Symbol:CKS2��
NCBI Official Synonym Symbols:CKSHS2��
NCBI Protein Information:cyclin-dependent kinases regulatory subunit 2; CKS-2; CDC28 protein kinase 2; CKS1(S. cerevisiae Cdc28/Cdc2 kinase subunit) homolog-2
UniProt Protein Name:Cyclin-dependent kinases regulatory subunit 2
Protein Family:Cyclin-dependent kinases regulatory
UniProt Gene Name:CKS2��
UniProt Entry Name:CKS2_HUMAN
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