Enzymes Recombinant Proteins

Human CKMBITII Recombinant Protein (RPPB2484)

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SKU:
RPPB2484
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Enzymes

Description

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Product Name:Human CKMBITII Recombinant Protein
Product Code:RPPB2484
Size:50µg
Species:Human
Target:CKMBITII
Synonyms:Creatine Kinase MB Isoenzyme Type-II, CKMBITII, CKMBI, CKMB.
Source:Pichia Pastoris
Physical Appearance:Sterile Filtered colourless liquid formulation.
Formulation:Each mg of protein contains 20mM Tris-HCl, pH-6.8, 1mM EDTA and 1mM DTT, 50% (v/v) glycerol.
Stability:CKMBITII although stable at 15°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.
Biological Activity:The enzyme activity measured by kinetic assay at 340nm was 884.6 IU/mg at 37 degrees.

CK-MB Type II possesses the naturally occurring carboxy-terminal amino acid lysine.This occurs during a myocardial infarct (MI or heart attack) when CK-MB Type II is released from damaged heart muscle, and the C-terminal lysine is cleaved in the blood stream, thus creating CK-MB Type I. This difference can be exploited in diagnosis of an MI.

CKMBITII Human Recombinant produced in Pichia Pastoris reacts with polyclonal antibodies to MB Isoenzyme in ELISA.

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