Human CISD1 Recombinant Protein (RPPB3188)
- SKU:
- RPPB3188
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NZ45
Description
| Product Name: | Human CISD1 Recombinant Protein |
| Product Code: | RPPB3188 |
| Size: | 20µg |
| Species: | Human |
| Target: | CISD1 |
| Synonyms: | CDGSH Iron Sulfur Domain 1, Chromosome 10 Open Reading Frame 70, CDGSH Iron Sulfur Domain-Containing Protein 1, Zinc Finger CDGSH-Type Domain 1, C10orf70, ZCD1, MitoNEET , MDS029. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CISD1 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSKRFYVKD HRNKAMINLH IQKDNPKIVH AFDMEDLGDK AVYCRCWRSK KFPFCDGAHT KHNEETGDNV GPLIIKKKET |
CISD1 protein holds a CDGSH iron-sulfur domain and is known to bind a redox-active [2Fe-2S] cluster. CISD1 is restricted to the outer membrane of mitochondria and takes part in oxidation regulation.
CISD1 Human Recombinant produced in E. coli is a single polypeptide chain containing 100 amino acids (32-108) and having a molecular mass of 11.4 kDa.CISD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ZCD1: Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 10q21.1 Cellular Component: mitochondrion |
| NCBI Summary: | This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q9NZ45 |
| NCBI GenInfo Identifier: | 25453105 |
| NCBI Gene ID: | 55847 |
| NCBI Accession: | Q9NZ45.1 |
| UniProt Secondary Accession: | Q9NZ45,Q1X902, |
| UniProt Related Accession: | Q9NZ45 |
| Molecular Weight: | 12kDa |
| NCBI Full Name: | CDGSH iron-sulfur domain-containing protein 1 |
| NCBI Synonym Full Names: | CDGSH iron sulfur domain 1 |
| NCBI Official Symbol: | CISD1�� |
| NCBI Official Synonym Symbols: | ZCD1; MDS029; C10orf70; mitoNEET�� |
| NCBI Protein Information: | CDGSH iron-sulfur domain-containing protein 1 |
| UniProt Protein Name: | CDGSH iron-sulfur domain-containing protein 1 |
| UniProt Synonym Protein Names: | MitoNEET |
| Protein Family: | CDGSH iron-sulfur domain-containing protein |
| UniProt Gene Name: | CISD1�� |
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