Human CHRM2 Full-Length Bioactive Membrane Protein (HDFP092)
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- SKU:
- HDFP092
Description
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| Product name | Human CHRM2 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP092 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | CHRM2 |
| Uniprot: | P08172 |
| Description: | Human CHRM2 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length CHRM2 protein has a MW of 51.5 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | HM2 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
Additional Information
Product Type: |
Recombinant Protein |
Protein Type: |
Full-Length Bioactive Membrane Protein |
Species: |
Human |
Uniprot: |
P08172 |
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