Human CFL1 / Cofilin ELISA Kit

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SKU:
HUFI01488
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P23528
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
CFL1, Cofilin 1, Non-Muscle, Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform
Reactivity:
Human
Research Area:
Cell Biology

Description

Human CFL1 / Cofilin ELISA Kit

CFL1 / Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. CFL1 / Cofilin is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. Increased phosphorylation of CFL1 / Cofilin by kinases aids in Rho-induced reorganization of the actin cytoskeleton. Diseases associated with CFL1 / Cofilin include Corticobasal Degeneration and Smith-Lemli-Opitz Syndrome.

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