Human CFHR5 Recombinant Protein (RPES0933)

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SKU:
RPES0933
Product Type:
Recombinant Protein
Species:
Human

Description

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Human CFHR5 Recombinant Protein

Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.

Product Name:Human CFHR5 Recombinant Protein (RPES0933)
Product Code:RPES0933
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Complement factor H-related protein 5,CFHR5,CFHL5,FHR5
Accession:Q9BXR6
Sequence:Glu19-Glu569
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Complement Factor H-Related 5 is produced by our Mammalian expression system and the target gene encoding Glu19-Glu569 is expressed with a 6His tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:63.5 kDa
AP Mol Mass:61 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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