Human CENPA / Centromere Protein A ELISA Kit

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SKU:
HUFI02309
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P49450
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
CENPA
Reactivity:
Human
Research Area:
Cell Cycle

Description

Human CENPA / Centromere Protein A ELISA

CENPA is expressed in all body tissues but it is most prevalent in reproductive tissue such as ovaries, testicles and embryos. In cancer, it has been observed that cells mutated in genes coding for histone-modifying enzymes - such as CBX5 and MLL2 - result in abnormal CENPA production. This causes errors in chromosome segregation and could result in chromosomal instability which can increase cancer prevalence. An important paralog of this gene is H3C10. Diseases associated with CENPA include Crest Syndrome and Dyskinesia Of Esophagus

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