Cell Death Recombinant Proteins

Human CEACAM5/CEA Recombinant Protein (RPES0336)

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SKU:
RPES0336
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death

Description

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Human CEACAM5/CEA Recombinant Protein

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5; also called CEA and CD66e; is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells; and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas; and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.

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