Human Cdk8 ELISA Kit

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SKU:
HUFI02304
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P49336
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
CDK8, Protein kinase K35, CDK8 protein kinase, Cell division protein kinase 8, cyclin-dependent kinase 8, K35, Mediator complex subunit CDK8, Mediator of RNA polymerase II transcription subunit CDK8, Protein kinase K35
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human Cdk8 ELISA Kit

CDK8 (Cyclin Dependent Kinase 8) encodes a protein that belongs to the cyclin-dependent kinase family. Cdk8 has been shown to interact with Cyclin A2, CDK7, CDC25A, p27Kip1. The protein is a serine/threonine kinase and is involved in the G1/S transition of the cell cycle. Mutations in CDK8 have been associated with lung cancer. Diseases associated with CDK8 include Intellectual Developmental Disorder With Hypotonia And Behavioral Abnormalities and Ebstein Anomaly. Pathways associated with CDK8 include Signaling by NOTCH1 and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha.

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