Human CD80/B7 Recombinant Protein (RPES1381)

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SKU:
RPES1381
Product Type:
Recombinant Protein
Species:
Human

Description

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Human CD80/B7 Recombinant Protein

B7-1 (CD80) is a cell surface immunoglobulin superfamily member that is expressed on the surfaces of antigen presenting cells such as activated B cells, macrophages, and dendritic cells. As costimulatory ligands; B7-1 which exists predominantly as dimer and the related protein B7-2; interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells; and thus constitute one of the dominant pathways that regulate T cell activation and tolerance; cytokine production; and the generation of CTL. The B7/CD28/CTLA4 pathway has the potential to both stimulate and dampen immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas. Human CD80/B7 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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