Human CD8 alpha / CD8A ELISA Kit

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SKU:
HUFI00839
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P01732
Sensitivity:
37.5pg/ml
Range:
62.5-4000pg/ml
ELISA Type:
Sandwich
Synonyms:
CD8A, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8, Leu-2
Reactivity:
Human
Research Area:
Immunology

Description

Human CD8 alpha / CD8A ELISA Kit

The CD8 antigen is a cell-surface glycoprotein present on virtually all cytotoxic T lymphocytes that helps them interact efficiently with other cells. The CD8 antigen functions as a coreceptor for the T-cell receptor on the T lymphocyte, which recognizes antigens presented by an antigen presenting cell in the context of class I MHC molecules. The coreceptor is a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains have a high degree of homology to immunoglobulin variable light chains. The different protein isoforms of this gene are determined by whether or not they have a transmembrane domain and, as a result, whether they are membrane-anchored or secreted proteins. A CD8 associated disorders is Herpes Zoster. Innate lymphoid cell differentiation and IL12-mediated signaling events are among the pathways CD8 is involved in.

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