CD Antigens Recombinant Proteins

Human CD72 Recombinant Protein (RPPB3089)

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SKU:
RPPB3089
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P21854
Research Area:
CD Antigens

Description

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Product Name:Human CD72 Recombinant Protein
Product Code:RPPB3089
Size:5µg
Species:Human
Target:CD72
Synonyms:B-cell differentiation antigen CD72, Lyb-2, CD72, LYB2, CD72b.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:CD72 at 100�g/ml in 50mM Tris-HCl, pH7.5, 10mM L-glutathione (reduced).
Stability:Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.

CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface moleculaes such as the asialoglycoprotein receptors, CD23 and the Kupffer cell recpeotr. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.

CD72 Human Recombinant (aa 1-98) expressed in E.coli, shows a 38 kDa band on SDS-PAGE. The CD72 is purified by proprietary chromatographic techniques.

UniProt Protein Function:CD72: Plays a role in B-cell proliferation and differentiation.
UniProt Protein Details:

Protein type:Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:protein binding; receptor binding

Biological Process: cell adhesion

UniProt Code:P21854
NCBI GenInfo Identifier:116029
NCBI Gene ID:971
NCBI Accession:P21854.1
UniProt Related Accession:P21854
Molecular Weight:40,220 Da
NCBI Full Name:B-cell differentiation antigen CD72
NCBI Synonym Full Names:CD72 molecule
NCBI Official Symbol:CD72��
NCBI Official Synonym Symbols:LYB2; CD72b��
NCBI Protein Information:B-cell differentiation antigen CD72
UniProt Protein Name:B-cell differentiation antigen CD72
UniProt Synonym Protein Names:Lyb-2; CD_antigen: CD72
Protein Family:B-cell differentiation antigen
UniProt Gene Name:CD72��
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