CD Antigens Recombinant Proteins

Human CD58 Recombinant Protein (RPPB3082)

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RPPB3082

Description

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Product Name:Human CD58 Recombinant Protein
Product Code:RPPB3082
Size:20µg
Species:Human
Target:CD58
Synonyms:ag3, LFA-3, LFA3, CD58 molecule, Lymphocytefunction-associated antigen 3, Ag3, Surfaceglycoprotein LFA-3.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:CD58 protein solution (1mg/ml) containing 20mM Phosphatebuffer and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHHSSGLVPRGSH MGSFSQQIYGVVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEMESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYFKMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR

CD58 is part of the immunoglobulin superfamily. CD58 is a ligand of the T lymphocyte CD2 protein, and is invloved in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane.

CD58 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (29-215 a.a) and having a molecular mass of 23.8kDa.CD58 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques

UniProt Protein Function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
NCBI Summary:This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
UniProt Code:P19256
NCBI GenInfo Identifier:126225
NCBI Gene ID:965
NCBI Accession:P19256.1
UniProt Secondary Accession:P19256,Q5U053, Q6IB65, Q96KI9, A8K7G5,
UniProt Related Accession:P19256
Molecular Weight:27,960 Da
NCBI Full Name:Lymphocyte function-associated antigen 3
NCBI Synonym Full Names:CD58 molecule
NCBI Official Symbol:CD58��
NCBI Official Synonym Symbols:ag3; LFA3; LFA-3��
NCBI Protein Information:lymphocyte function-associated antigen 3
UniProt Protein Name:Lymphocyte function-associated antigen 3
UniProt Synonym Protein Names:Surface glycoprotein LFA-3; CD_antigen: CD58
Protein Family:Lymphocyte function-associated antigen
UniProt Gene Name:CD58��
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P19256
Research Area:
CD Antigens
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