Human CD57 Monoclonal Antibody (Biotin Conjugated) [HNK-1](AGEL0267)

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SKU:
AGEL0267
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgM
Clone:
HNK-1
Conjugation:
Biotin
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Human CD57 Monoclonal Antibody (Biotin Conjugated)
Antibody Code:AGEL0267
Size:100µg
Clone:HNK-1
Synonyms:Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, B3GAT1, GlcAT-P, GlcUAT-P, GLCATP
Host Species:Mouse
Species Reactivity:Human
Applications:FC
Concentration:1mg/mL
Isotype:IgM
Conjugation:Biotin
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:27087
Uniprot:Q9P2W7
Background:CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).
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