Immune Checkpoint Recombinant Proteins

Human CD46 Recombinant Protein (His Tag) (HDPT0119)

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SKU:: HDPT0119
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human CD46 Recombinant Protein (His Tag)

Description:	The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Product name:	Human CD46 Recombinant Protein (His Tag)
Synonyms:	CD46,AHUS2,MCP,MIC10,TLX,TRA2.10
Type:	protein
Size:	50 µg
Name:	CD46
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	> 95%
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-6×His tag
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	CD46（Cys35-Asp328）+6×His tag
Gene ID:	4179
Uniprot:	P15529
Molecular Weight:	55-70 kDa