Human CD46 / MCP ELISA Kit

(No reviews yet) Write a Review
SKU:
HUFI01175
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P15529
Sensitivity:
4.688pg/ml
Range:
7.813-500pg/ml
ELISA Type:
Sandwich
Synonyms:
MCP, CD46, Membrane Cofactor Protein, AHUS2, MIC10, CD46 molecule, complement regulatory protein, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Reactivity:
Human
Research Area:
Immunology

Description

Human CD46 / MCP ELISA Kit

CD46/MCP has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects autologous cells against complement-mediated injury. CD46/MCP may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46/MCP also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. Mutations in CD46/MCP have been associated with susceptibility to hemolytic uremic syndrome. CD46/MCP related pathways include Immune response Lectin induced complement pathway and NF-kappaB Signaling.

View AllClose

0 Reviews

View AllClose