Human CD45RA Monoclonal Antibody (Biotin Conjugated) [HI100](AGEL0228)

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SKU:
AGEL0228
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
HI100
Conjugation:
Biotin
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Human CD45RA Monoclonal Antibody (Biotin Conjugated)
Antibody Code:AGEL0228
Size:100µg
Clone:HI100
Synonyms:Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45
Host Species:Mouse
Species Reactivity:Human
Applications:FC
Concentration:1mg/mL
Isotype:IgG2b
Conjugation:Biotin
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:5788
Uniprot:P08575
Background:CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
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